Resources

C2D2 is dedicated to providing researchers with medicinal chemistry knowledge as well as alerting faculty to additional funding opportunities.

C2D2 Reference Library

Selected Medchem References

• “Can the pharmaceutical industry reduce attrition rates” Landis, J., Nature Reviews Drug Discovery 2004, 3, 711
• The role of the medicinal chemist in drug discovery then and now, Lombardino, J.G., Nature Reviews Drug Discovery, 2004, 3, 853
• "Road map to oral bioavailability”, Thomas, V.H., Exp Op Drug Met. Toxicol, 2006 2(4), 591
• “Molecular Properties that Influence the Oral Bioavailability of Drug Candidates”, J. Med. Chem, 2002, 45, 2615
• “Target Selection in Drug Discovery”, Knowles, J., Nat Rev. Drug Disc, 2003, 2, 63
• “Identification and evaluation of the molecular properties related to preclinical optimization and clinical fate”, Blake, J.F., Medicinal Chemistry, 2005, 1,649
• “NIH Translational Programs for Assisting Pre-Clinical Drug Discovery and Development”
• “Getting Physical in Drug Discovery: A Contemporary Perspective on Solubility and Hydrophobicity”